When using a cleanser like Cetaphil, your going to remove dirt and oil as well as balance the PH of your skin. It's best to first remove your make-up that way the cleanser can clean your skin and do it's job. I love Sephora Collection cleansing wipes. They are hypo-allergenic and contain an ingredient called Hydrosen + which will help your skin maintain moisture levels and prevent overdrying. They retail at a killer $9! They're also great for your gym bag, or in the morning when you maybe don't need to use a full on cleanser to prep your skin.
Hope that helps!